We propose a practical implementation of a universal quantum computer that uses local fermionic modes (LFM) rather than qubits. Our design consists of quantum dots tunnel coupled by a hybrid superconducting island together with a tunable capacitive coupling between the dots. We show that coherent control of Cooper pair splitting, elastic cotunneling, and Coulomb interactions allows us to implement the universal set of quantum gates defined by Bravyi and Kitaev. Finally, we discuss possible limitations of the device and list necessary experimental efforts to overcome them.